1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → 6-Bromo-2-[4-(3-trifluoromethylpyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([Cl:9])[n:8]2)[cH:10][cH:11]1.[F:12][C:13]([c:14]1[c:15]([N:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[n:16][cH:17][cH:18][cH:19]1)([F:26])[F:27]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([N:23]3[CH2:22][CH2:21][N:20]([c:15]4[c:14]([C:13]([F:12])([F:26])[F:27])[cH:19][cH:18][cH:17][n:16]4)[CH2:25][CH2:24]3)[nH:8]2)[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-0cc649753e4b49f38fb846049dc6768f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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