4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine → HCID 46701187, compound
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2.[CH3:26][C:27]1([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32][B:33]([c:34]2[cH:35][n:36][n:37]([C:39]3([CH2:44][C:45]#[N:46])[CH2:40][CH2:41][CH2:42][CH2:43]3)[cH:38]2)[O:47]1>>[c:2]1(-[c:34]2[cH:35][n:36][n:37]([C:39]3([CH2:44][C:45]#[N:46])[CH2:40][CH2:41][CH2:42][CH2:43]3)[cH:38]2)[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2Participants
3
Sources & evidence
- ORD record
- ord-525bcc71fceb404fb06bfb6cbf3f108b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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