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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2327625Generated: October 27, 2026

Hydrochloric Acid → 5-(4-Chloro-phenyl)-2-{4-[2-(4-isopropyl-piperidin-1-yl)-ethoxy]-3-methyl-phenylethynyl}-pyridine

https://huagongshe.com/reaction/2327625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylethylamineHCID 81531—
ReactantPiperidine, 4-(1-methylethyl)-HCID 140569—
Reactant2-{4-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]-2-methylphenoxy}ethyl methanesulfonateHCID 86594683—
Product5-(4-Chloro-phenyl)-2-{4-[2-(4-isopropyl-piperidin-1-yl)-ethoxy]-3-methyl-phenylethynyl}-pyridineHCID 59835742—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-622b6d9507b240c6a8451d52c6c48449
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)