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HRID232805

反应详情

EQUATION

反应方程式

HRID 232805 的结构方程式

REACTANTS

反应物

2
结构：CI
HCID6328

Methyl iodide

CH3I

结构：CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(=O)c5cccnc5)CC[C@]4(C)[C@H]3CC[C@]12C
HCID54438032

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(=O)C5=CC=CN(C)C5)CC[C@]4(C)[C@H]3CC[C@]12C.[I-]
HCID131718039

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A mixture of 3α-nicotinoyloxy-5α-pregnan-20-one (770 mg, 421 g/m, 1.8 mmol) and methyliodide (3.0 mL, 141 g/m, -20 mmol) in 30 mL of acetone was refluxed gently for 17 hours. The reaction mixture was concentrated in vacuo to give the crude product.

WORKUP

后处理

  1. temperaturewas refluxed gently for 17 hours
  2. concentrationThe reaction mixture was concentrated in vacuo