Methanol → 3-[(4-Chloro-benzyl)-(2-hydroxy-ethyl)-amino]-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[BH4-:27].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][C:15](=[O:16])[O:17][CH3:18])[CH2:19][c:20]2[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]2)[CH2:11][CH2:12]1.[CH3:29][OH:30].[Na+:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH2:15][OH:16])[CH2:19][c:20]2[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]2)[CH2:11][CH2:12]1Participants
5
Sources & evidence
- ORD record
- ord-1227cf9214304941b89211a3e6a39e09
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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