Acetate → 1-[7-(Cyclopentylamino)-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]ethanone

HRID 2328379Notes

Reaction equation

HRID 2328379 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[CH:28]1([NH2:33])[CH2:29][CH2:30][CH2:31][CH2:32]1.[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[n:7]1[n:8][c:9](-[c:14]1[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1)[c:10]2[C:11]([CH3:12])=[O:13].[Cs+:26].[Cs+:27].[O-:47][C:48]([CH3:49])=[O:50].[O-:51][C:52]([CH3:53])=[O:54].[OH2:55].[Pd+2:46]>>[c:2]1([NH:33][CH:28]2[CH2:29][CH2:30][CH2:31][CH2:32]2)[cH:3][cH:4][cH:5][c:6]2[n:7]1[n:8][c:9](-[c:14]1[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1)[c:10]2[C:11]([CH3:12])=[O:13]

Participants

10

Reactant 9

HCID 175Acetate2×HCID 962WaterHCID 1140TolueneHCID 2906CyclopentylamineHCID 3283Diethyl EtherHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 223500511-[7-(Chloro)-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]ethanone

Product 1

HCID 223500531-[7-(Cyclopentylamino)-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]ethanone

Sources & evidence

ORD record
ord-4e48987bae494ffd93c23948e153b94c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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