2-Naphthylamine → 4-[4-(Naphthalen-2-ylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([C:20](=[O:21])[OH:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[C:34]([O:35][C:36]([N:37]1[CH2:38][CH2:39][N:40]([c:41]2[cH:42][cH:43][c:44]([C:45](=[O:46])[NH:47][c:48]3[cH:49][cH:50][cH:51][c:52]([C:53]([CH3:54])([CH3:55])[CH3:56])[cH:57]3)[cH:58][cH:59]2)[CH2:60][CH2:61]1)=[O:62])([CH3:63])([CH3:64])[CH3:65].[cH:23]1[c:24]([NH2:33])[cH:25][cH:26][c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([C:20](=[O:21])[NH:33][c:24]3[cH:23][c:32]4[c:27]([cH:26][cH:25]3)[cH:28][cH:29][cH:30][cH:31]4)[cH:18][cH:19]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0c4e982e23494d4ab74aa69a7894d357
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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