4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran → 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran
Reaction equation
[C:1](#[N:2])[C:3]1([c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1.[CH3:16][c:17]1[n:18](-[c:22]2[cH:23][cH:24][c:25]([CH2:26][Cl:27])[cH:28][cH:29]2)[cH:19][cH:20][n:21]1>>[C:1](#[N:2])[C:3]1([c:9]2[cH:10][c:11]([O:15][CH2:26][c:25]3[cH:24][cH:23][c:22](-[n:18]4[c:17]([CH3:16])[n:21][cH:20][cH:19]4)[cH:29][cH:28]3)[cH:12][cH:13][cH:14]2)[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1Participants
3
Sources & evidence
- ORD record
- ord-8e12a80407634074b6f48507207413f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…