(+-)-2-Mercaptopropionic acid → 11-(1-Carboxyethylthio)-2-(quinolin-2-yl)methoxy-6,11-dihydrodibenz[b,e]oxepine
Reaction equation
O[CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([O:17][CH2:18][C:19]3[CH:28]=[CH:27][C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[N:20]=3)=[CH:16][C:3]1=2.[SH:29][CH:30]([CH3:34])[C:31]([OH:33])=[O:32]>>[C:31]([CH:30]([S:29][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([O:17][CH2:18][C:19]3[CH:28]=[CH:27][C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[N:20]=3)=[CH:16][C:3]1=2)[CH3:34])([OH:33])=[O:32]Participants
3
Procedure
11-Hydroxy-2-(quinolin-2-yl)methoxy-6,11-dihydrodibenz[b,e]oxepine and 2-mercaptopropionic acid were used and reacted in the same manner as in Example 1 to obtain the title compound.
Workup
- customreacted in the same manner as in Example 1
Sources & evidence
- ORD record
- ord-d289626cbf8d42f6b070e2b66603646f
- Source dataset
- uspto-grants-1997_01
- Patent number
- US05591752
Reaction notes
Loading…