3-Mercaptopropionic Acid → HCID 23359238, compound

HRID 232863Notes

Reaction equation

HRID 232863 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH2:12][O:13][C:14]3[CH:31]=[CH:30][C:17]4[O:18][CH2:19][C:20]5[C:27]([C:28]#[N:29])=[CH:26][CH:25]=[CH:24][C:21]=5[CH:22](O)[C:16]=4[CH:15]=3)=[N:9]2)=[CH:4][C:3]=1[F:32].[SH:33][CH2:34][CH2:35][C:36]([OH:38])=[O:37]>>[C:36]([CH2:35][CH2:34][S:33][CH:22]1[C:21]2[CH:24]=[CH:25][CH:26]=[C:27]([C:28]#[N:29])[C:20]=2[CH2:19][O:18][C:17]2[CH:30]=[CH:31][C:14]([O:13][CH2:12][C:8]3[CH:7]=[CH:6][C:5]4[C:10](=[CH:11][C:2]([Cl:1])=[C:3]([F:32])[CH:4]=4)[N:9]=3)=[CH:15][C:16]1=2)([OH:38])=[O:37]

Participants

3

Reactant 2

HCID 65143-Mercaptopropionic AcidHCID 23359180HCID 23359180, compound

Product 1

HCID 23359238HCID 23359238, compound

Procedure

2-(7-Chloro-6-fluoroquinolin-2-yl)methoxy-7-cyano-11-hydroxy-6,11-dihydrodibenz[b,e]oxepine and 3-mercaptopropionic acid were used and reacted in the same manner as in Example 1 to obtain the title compound.

Workup

  1. customreacted in the same manner as in Example 1

Sources & evidence

ORD record
ord-aea2ce941f65419f8de822afe4b1b1df
Source dataset
uspto-grants-1997_01
Patent number
US05591752

Reaction notes

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