HRID232864

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6514

3-Mercaptopropanoic acid

C3H6O2S

结构：CC(=O)CCc1ccc2c(c1)COc1ccc(OCc3ccc4cc(F)c(Cl)cc4n3)cc1C2O

HCID23359136

未命名化合物

PRODUCTS

生成物

结构：CC(=O)CCc1ccc2c(c1)COc1ccc(OCc3ccc4cc(F)c(Cl)cc4n3)cc1C2SCCC(=O)O

HCID23359164

未命名化合物

PROCEDURE

实验过程

2-(7-Chloro-6-fluoroquinolin-2-yl)methoxy-11-hydroxy-8-(2-acetylethyl)-6,11-dihydrodibenz[b,e]oxepine and 3-mercaptopropionic acid were used and reacted in the same manner as in Example 1 to obtain the title compound.

WORKUP

后处理

customreacted in the same manner as in Example 1

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6cbb01c235ec40dea3e2acc8f6d6dbff
来源数据集: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05591752
来源说明: uspto-grants-1997_01

反应 SMILES

[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH2:12][O:13][C:14]3[CH:34]=[CH:33][C:17]4[O:18][CH2:19][C:20]5[CH:27]=[C:26]([CH2:28][CH2:29][C:30](=[O:32])[CH3:31])[CH:25]=[CH:24][C:21]=5[CH:22](O)[C:16]=4[CH:15]=3)=[N:9]2)=[CH:4][C:3]=1[F:35].[SH:36][CH2:37][CH2:38][C:39]([OH:41])=[O:40]>>[C:39]([CH2:38][CH2:37][S:36][CH:22]1[C:21]2[CH:24]=[CH:25][C:26]([CH2:28][CH2:29][C:30](=[O:32])[CH3:31])=[CH:27][C:20]=2[CH2:19][O:18][C:17]2[CH:33]=[CH:34][C:14]([O:13][CH2:12][C:8]3[CH:7]=[CH:6][C:5]4[C:10](=[CH:11][C:2]([Cl:1])=[C:3]([F:35])[CH:4]=4)[N:9]=3)=[CH:15][C:16]1=2)([OH:41])=[O:40]