1,4-Dioxaspiro[4.5]decan-8-one → HCID 68004010, compound

HRID 2329062Notes

Reaction equation

HRID 2329062 reaction equation
[Br:17][c:18]1[s:19][c:20]([CH:21]([CH3:22])[CH3:23])[n:24][cH:25]1.[NH:37]1[CH2:38][CH:39]([NH:41][C:42]([CH2:43][NH:44][c:45]2[n:46][cH:47][n:48][c:49]3[cH:50][cH:51][c:52]([C:55]([F:56])([F:57])[F:58])[cH:53][c:54]23)=[O:59])[CH2:40]1.[O:26]1[C:27]2([CH2:28][CH2:29][C:30](=[O:31])[CH2:32][CH2:33]2)[O:34][CH2:35][CH2:36]1.[OH:1][C:2]1([c:9]2[cH:10][n:11][c:12]([CH:14]([CH3:15])[CH3:16])[s:13]2)[CH2:3][CH2:4][C:5](=[O:8])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:9]2[cH:10][n:11][c:12]([CH:14]([CH3:15])[CH3:16])[s:13]2)[CH2:3][CH2:4][CH:5]([N:37]2[CH2:38][CH:39]([NH:41][C:42]([CH2:43][NH:44][c:45]3[n:46][cH:47][n:48][c:49]4[cH:50][cH:51][c:52]([C:55]([F:56])([F:57])[F:58])[cH:53][c:54]34)=[O:59])[CH2:40]2)[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 20696775HCID 20696775, compoundHCID 595561884-Hydroxy-4-(2-isopropylthiazol-5-yl)cyclohexanoneHCID 68003594N-(azetidin-3-yl)-2((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide

Product 1

HCID 68004010HCID 68004010, compound

Sources & evidence

ORD record
ord-05333a903f844592ad5180f471c0fd8f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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