2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-(5-tert-butyl-2H-pyrazol-3-yl)-carbamic acid 2,2,2-trichloro-ethyl ester → 1-{5-tert-Butyl-2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2H-pyrazol-3-yl}-3-{4-[7-(4-methanesulfonyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-benzyl}-urea
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[n:14]([cH:15][cH:16]2)[c:17](-[c:20]2[cH:21][cH:22][c:23]([CH2:24][NH2:25])[cH:26][cH:27]2)[cH:18][n:19]3)[cH:9][cH:10]1.[Cl:28][C:29]([Cl:30])([Cl:53])[CH2:54][O:31][C:32]([NH:33][c:34]1[n:35]([CH2:43][CH2:44][O:45][Si:46]([CH3:47])([CH3:48])[C:49]([CH3:50])([CH3:51])[CH3:52])[n:36][c:37]([C:39]([CH3:40])([CH3:41])[CH3:42])[cH:38]1)=[O:55]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[n:14]([cH:15][cH:16]2)[c:17](-[c:20]2[cH:21][cH:22][c:23]([CH2:24][NH:25][C:32](=[O:31])[NH:33][c:34]4[n:35]([CH2:43][CH2:44][O:45][Si:46]([CH3:47])([CH3:48])[C:49]([CH3:50])([CH3:51])[CH3:52])[n:36][c:37]([C:39]([CH3:40])([CH3:41])[CH3:42])[cH:38]4)[cH:26][cH:27]2)[cH:18][n:19]3)[cH:9][cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-54bbac9bfddf460ba92f9d8dba025e6e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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