Benzyl Alcohol → 3-{2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(benzyloxycarbonyl)methoxypyridine

HRID 2329304Notes

Reaction equation

HRID 2329304 reaction equation
[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([O:11][CH2:12][C:13](=[O:14])[O:15][CH3:16])[n:7][cH:8][cH:9][cH:10]2)[cH:17][c:18](-[n:22]2[c:23](=[O:34])[n:24]([CH3:33])[c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][c:27]2=[O:28])[c:19]([F:21])[cH:20]1.[Na+:35].[Na+:36].[O-:37][C:38](=[O:39])[O-:40].[OH:41][CH2:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([O:11][CH2:12][C:13](=[O:14])[O:15][CH2:16][c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[n:7][cH:8][cH:9][cH:10]2)[cH:17][c:18](-[n:22]2[c:23](=[O:34])[n:24]([CH3:33])[c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][c:27]2=[O:28])[c:19]([F:21])[cH:20]1

Participants

6

Reactant 5

HCID 244Benzyl AlcoholHCID 923Sodium ion2×HCID 1140TolueneHCID 19660Carbonate IonHCID 120567393-[2-Chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl)phenoxy]-2-(methoxycarbonylmethoxy)pyridine

Product 1

HCID 186192133-{2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(benzyloxycarbonyl)methoxypyridine

Sources & evidence

ORD record
ord-7e988df57aa8419ea327e57ad0c7741b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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