Methanol → 6-[2,6-Dichloro-4-(2-hydroxy-ethyl)-phenoxy]-4-isopropyl-2-methyl-pyridazin-3-one

HRID 2329306Notes

Reaction equation

[CH3:29][OH:30].[Cl:1][c:2]1[cH:3][c:4]([CH2:21][CH2:22][O:23][C:24](=[O:25])[CH3:26])[cH:5][c:6]([Cl:20])[c:7]1[O:8][c:9]1[n:10][n:11]([CH3:19])[c:12](=[O:18])[c:13]([CH:15]([CH3:16])[CH3:17])[cH:14]1.[Na+:28].[OH-:27]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:21][CH2:22][OH:23])[cH:5][c:6]([Cl:20])[c:7]1[O:8][c:9]1[n:10][n:11]([CH3:19])[c:12](=[O:18])[c:13]([CH:15]([CH3:16])[CH3:17])[cH:14]1

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium ion

HCID 961Hydroxide

HCID 59834451Acetic acid 2-[3,5-dichloro-4-(5-isopropyl-1-methyl-6-oxo-1,6-dihydro-pyridazin-3-yloxy)-phenyl]-ethyl ester

Product 1

HCID 598344796-[2,6-Dichloro-4-(2-hydroxy-ethyl)-phenoxy]-4-isopropyl-2-methyl-pyridazin-3-one

Sources & evidence

ORD record: ord-43d4f185a1784d96b270caf552444145
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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