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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2329523Generated: October 25, 2026

Water → 2-(3-{2-Methoxy-6-[(thiophen-3-ylmethyl)-amino]-pyrimidin-4-yl}-phenyl)-2-methyl-propionic acid

https://huagongshe.com/reaction/2329523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
ReactantCesium cationHCID 104967—
Reactant2-(3-Boronophenyl)-2-methylpropanoic acidHCID 44248997—
Reactant(6-Chloro-2-methoxy-pyrimidin-4-yl)-thiophen-3-ylmethyl-amineHCID 86615704—
Product2-(3-{2-Methoxy-6-[(thiophen-3-ylmethyl)-amino]-pyrimidin-4-yl}-phenyl)-2-methyl-propionic acidHCID 11610662—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-ac2c35fab3684054991cb0c3ec517be5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)