5-Methylisoxazole-3-carbonyl chloride → 6-(2-Fluoro-4-iodophenylamino)-1,3-dimethyl-5-(5-methylisoxazole-3-carbonyl)pyrimidine-2,4(1H,3H)-dione

HRID 2329655Notes

Reaction equation

HRID 2329655 reaction equation
[CH3:29][c:30]1[cH:31][c:32]([C:35]([Cl:36])=[O:37])[n:33][o:34]1.[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[O:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[c:32]3[cH:31][c:30]([CH3:29])[o:34][n:33]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1

Participants

3

Reactant 2

HCID 27368945-Methylisoxazole-3-carbonyl chlorideHCID 59259226Phenyl 6-(2-fluoro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Product 1

HCID 251089576-(2-Fluoro-4-iodophenylamino)-1,3-dimethyl-5-(5-methylisoxazole-3-carbonyl)pyrimidine-2,4(1H,3H)-dione

Sources & evidence

ORD record
ord-1e639d234d2e47d8b6589c5d72846113
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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