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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 233011Generated: October 31, 2026

Trifluoroacetic acid → 4'-[(2-Ethyl-4-methyl-6-(3-chloro-5,6,7,8-tetrahydro-imidazo-[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic Acid

https://huagongshe.com/reaction/233011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67708508HCID 67708508—
SolventDichloromethaneHCID 6344—
Product4'-[(2-Ethyl-4-methyl-6-(3-chloro-5,6,7,8-tetrahydro-imidazo-[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic AcidHCID 19964727—

Reaction Steps

Prepared analogously to Example 208 from tert.butyl 4'-[(2-ethyl-4-methyl-6-(3-chloro-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05591762
Source datasetuspto-grants-1997_01
ORD IDord-98a66959900741ae9eec45da04a6414f
Source noteuspto-grants-1997_01