Boron tribromide → 5-{2-[2-Chloro-4-(4-fluoro-3-hydroxy-phenoxy)-phenyl]-1-hydroxy-1-trifluoromethyl-propyl}-1-methyl-1H-pyridin-2-one
Reaction equation
[B:34]([Br:35])([Br:36])[Br:37].[Cl:1][c:2]1[c:3]([CH:18]([C:19]([C:20]([F:21])([F:22])[F:23])([OH:24])[c:25]2[cH:26][cH:27][c:28](=[O:32])[n:29]([CH3:31])[cH:30]2)[CH3:33])[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([O:16][CH3:17])[c:12]([F:15])[cH:13][cH:14]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([CH:18]([C:19]([C:20]([F:21])([F:22])[F:23])([OH:24])[c:25]2[cH:26][cH:27][c:28](=[O:32])[n:29]([CH3:31])[cH:30]2)[CH3:33])[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([OH:16])[c:12]([F:15])[cH:13][cH:14]2)[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-382b247eeb894a458848a78dc518a9d9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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