6-bromo-8-cyclopentyl-2-methanesulfinyl-8H-pyrido[2,3-d]pyrimidin-7-one → 4-[6-(6-Bromo-8-cyclopentyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([S:10]([CH3:11])=[O:12])[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15].[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH2:30][N:31]([c:34]2[cH:35][n:36][c:37]([NH2:40])[cH:38][cH:39]2)[CH2:32][CH2:33]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([NH:40][c:37]3[n:36][cH:35][c:34]([N:31]4[CH2:30][CH2:29][N:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:33][CH2:32]4)[cH:39][cH:38]3)[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8aa640db344045709bc822966fdd3157
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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