1-(Bromomethyl)-2-(trifluoromethyl)benzene → 8-Bromo-3-methyl-7-(2-trifluoromethylbenzyl)-3,7-dihydropurine-2,6-dione
Reaction equation
[Br:1][c:2]1[n:3][c:4]2[n:5]([CH3:13])[c:6](=[O:12])[nH:7][c:8](=[O:11])[c:9]2[nH:10]1.[F:14][C:15]([c:16]1[c:17]([CH2:18][Br:19])[cH:20][cH:21][cH:22][cH:23]1)([F:24])[F:25]>>[Br:1][c:2]1[n:3][c:4]2[n:5]([CH3:13])[c:6](=[O:12])[nH:7][c:8](=[O:11])[c:9]2[n:10]1[CH2:18][c:17]1[c:16]([C:15]([F:14])([F:24])[F:25])[cH:23][cH:22][cH:21][cH:20]1Participants
3
Sources & evidence
- ORD record
- ord-20f2244364c542a9a4acf776e8825af9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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