反应详情

A slurry of benzimidazole (8.50 g, 36.3 mmol) in toluene (40 mL) at 0° C. was treated with 25.8 mL of a 2.8 M n-BuLi (72.2 mmol) solution in hexanes. This solution mixture was then refluxed for one day during which time the slurry became off-white. The slurry was then filtered over a medium glass frit and dried to give a white solid.

1. temperatureThis solution mixture was then refluxed for one day during which time the slurry
2. filtrationThe slurry was then filtered over a medium glass frit
3. customdried
4. customto give a white solid