2-Methylpyridine-5-boronic acid → 5-Amino-6'-methyl-3-trifluoromethyl-[2,3']bipyridinyl-6-carboxylic acid methyl ester
Reaction equation
[CH3:17][c:18]1[n:19][cH:20][c:21]([B:24]([OH:25])[OH:26])[cH:22][cH:23]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:16])[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11].[NH2:27][c:28]1[c:29]([C:30]([OH:31])=[O:32])[n:33][c:34](-[c:35]2[cH:36][cH:37][c:38]([F:39])[cH:40][cH:41]2)[c:42]([C:43]([F:44])([F:45])[F:46])[cH:47]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:21]2[cH:20][n:19][c:18]([CH3:17])[cH:23][cH:22]2)[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6e416f7121e340d9b9d779668b3a9bd4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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