Ethyl bromoacetate → tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperazine-1-carboxylate

HRID 2331664Notes

Reaction equation

HRID 2331664 reaction equation
[Br:20][CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26].[C:14](=[O:15])([O-:16])[O-:17].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[Cs+:18].[Cs+:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 7748Ethyl bromoacetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 22321826tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-0a914e4071d64d03b57680b81025392b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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