Dichloromethane → 2-Chloromethyl-8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine

HRID 2331775Notes

Reaction equation

HRID 2331775 reaction equation
[CH2:27]([Cl:28])[Cl:29].[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH3:17])[c:13]([CH2:15][OH:16])[n:14]3)[c:18]([CH3:22])[cH:19][cH:20][cH:21]1.[S:23]([Cl:24])([Cl:25])=[O:26]>>[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH3:17])[c:13]([CH2:15][Cl:25])[n:14]3)[c:18]([CH3:22])[cH:19][cH:20][cH:21]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 98826348-(2,6-Dimethylbenzylamino)-2-hydroxymethyl-3-methylimidazo[1,2-a]pyridine

Product 1

HCID 226726282-Chloromethyl-8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-73966e01258846e8bdc7ef31fdc9b6bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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