N1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamide → N1-(4-(2-(1-ethyl-1H-imidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-(2-methoxyphenyl)malonamide
Reaction equation
[CH2:39]([CH3:40])[n:41]1[cH:42][n:43][c:44](-[c:46]2[s:47][c:48]3[c:49]([n:50][cH:51][cH:52][c:53]3[O:54][c:55]3[cH:56][cH:57][c:58]([NH2:59])[cH:60][c:61]3[F:62])[cH:63]2)[cH:45]1.[F:1][c:2]1[cH:3][c:4]([NH:24][C:25]([CH2:26][C:27](=[O:28])[NH:29][c:30]2[c:31]([O:36][CH3:37])[cH:32][cH:33][cH:34][cH:35]2)=[O:38])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19]([CH3:20])[cH:21][cH:22][n:23]1)[s:17]2>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:25]([CH2:26][C:27](=[O:28])[NH:29][c:30]2[c:31]([O:36][CH3:37])[cH:32][cH:33][cH:34][cH:35]2)=[O:38])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:44]1[n:43][cH:42][n:41]([CH2:39][CH3:40])[cH:45]1)[s:17]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-956bd062b4bf4f3d91770ee70ca2dbc6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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