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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2331889Generated: October 30, 2026

Citric Acid → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester

https://huagongshe.com/reaction/2331889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantEthyl AcetateHCID 8857—
ReactantBorohydrideHCID 28123—
Reactant6-[3-(4-Fluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl esterHCID 86646254—
Product6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl esterHCID 66718131—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-be1113d021a94694bb40a926b53d1d73
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)