1,2-Dimethoxyethane → 4-[[2-(4-Pyrimidinyloxy)ethyl](2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

HRID 2331936Notes

Reaction equation

HRID 2331936 reaction equation
[CH3:29][O:30][CH2:31][CH2:32][O:33][CH3:34].[OH:1][CH2:2][CH2:3][N:4]([c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)[CH2:17][C:18]([F:19])([F:20])[F:21].[nH:22]1[cH:23][n:24][c:25](=[O:28])[cH:26][cH:27]1>>[O:1]([CH2:2][CH2:3][N:4]([c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)[CH2:17][C:18]([F:19])([F:20])[F:21])[c:25]1[n:24][cH:23][n:22][cH:27][cH:26]1

Participants

4

Reactant 3

HCID 80711,2-DimethoxyethaneHCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 178516534HCID 178516534, compound

Product 1

HCID 116180344-[[2-(4-Pyrimidinyloxy)ethyl](2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Sources & evidence

ORD record
ord-9c519f4f6c3040a78bb66b0ed4b128c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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