Acetonitrile → Methyl 6-amino-5-bromo-3-fluoropicolinate

HRID 2331966Notes

Reaction equation

HRID 2331966 reaction equation
[B-:13]([F:14])([F:15])([F:16])[F:17].[B-:18]([F:19])([F:20])([F:21])[F:22].[CH3:34][C:35]#[N:36].[Cl:23][CH2:24][N+:25]12[CH2:26][CH2:27][N+:28]([F:29])([CH2:30][CH2:31]1)[CH2:32][CH2:33]2.[NH2:1][c:2]1[c:3]([Br:12])[cH:4][cH:5][c:6]([C:8](=[O:9])[O:10][CH3:11])[n:7]1>>[NH2:1][c:2]1[c:3]([Br:12])[cH:4][c:5]([F:14])[c:6]([C:8](=[O:9])[O:10][CH3:11])[n:7]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 26255Tetrafluoroborate2×HCID 27249341-(Chloromethyl)-4-fluoro-1,4-diazoniabicyclo(2.2.2)octaneHCID 10704661Methyl 6-amino-5-bromopicolinate

Product 1

HCID 21873678Methyl 6-amino-5-bromo-3-fluoropicolinate

Sources & evidence

ORD record
ord-ec5a7840e1bc434cb8673b1b4cd344e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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