Sodium ion → (+/-)-3-{4-[4-(2-Methyl-piperidin-1-ylmethyl)-oxazol-2-yl]-phenyl}-pyridine

HRID 2332009Notes

Reaction equation

HRID 2332009 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][cH:10][c:11]([CH2:13][N:14]3[CH:15]([CH3:20])[CH2:16][CH2:17][CH2:18][CH2:19]3)[n:12]2)[cH:6][cH:7]1.[Na+:30].[Na+:31].[O-:32][C:33](=[O:34])[O-:35].[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1.[n:21]1[cH:22][c:23]([B:27]([OH:28])[OH:29])[cH:24][cH:25][cH:26]1>>[c:2]1(-[c:23]2[cH:22][n:21][cH:26][cH:25][cH:24]2)[cH:3][cH:4][c:5](-[c:8]2[o:9][cH:10][c:11]([CH2:13][N:14]3[CH:15]([CH3:20])[CH2:16][CH2:17][CH2:18][CH2:19]3)[n:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27343783-Pyridinylboronic acidHCID 11508283HCID 11508283, compound

Product 1

HCID 11537304(+/-)-3-{4-[4-(2-Methyl-piperidin-1-ylmethyl)-oxazol-2-yl]-phenyl}-pyridine

Sources & evidence

ORD record
ord-470c9debb93f40b592d3b463b8de32ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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