Pyridine → N1-{4-[4-amino-1-(1-methyl-4-piperidyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl}-4-(trifluoromethyl)benzamide
Reaction equation
[Cl:40][CH2:41][Cl:42].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9](=[O:10])[Cl:11])[cH:7][cH:8]1)([F:12])[F:13].[NH2:14][c:15]1[c:16]([O:38][CH3:39])[cH:17][c:18](-[c:21]2[n:22][n:23]([CH:31]3[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]3)[c:24]3[n:25][cH:26][n:27][c:28]([NH2:30])[c:29]23)[cH:19][cH:20]1.[cH:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9](=[O:10])[NH:14][c:15]2[c:16]([O:38][CH3:39])[cH:17][c:18](-[c:21]3[n:22][n:23]([CH:31]4[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]4)[c:24]4[n:25][cH:26][n:27][c:28]([NH2:30])[c:29]34)[cH:19][cH:20]2)[cH:7][cH:8]1)([F:12])[F:13]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-db727225a6e14b56813aa071cabaefee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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