Methanol → 3-(3-(4-(2-Fluoro-benzyloxy)-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine
Reaction equation
[CH3:32][OH:33].[F:23][c:24]1[c:25]([CH2:26][Br:27])[cH:28][cH:29][cH:30][cH:31]1.[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]2)[n:11][o:12]1.[Na+:22].[OH-:21]>>[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH2:26][c:25]3[c:24]([F:23])[cH:31][cH:30][cH:29][cH:28]3)[cH:18][cH:19]2)[n:11][o:12]1Participants
6
Sources & evidence
- ORD record
- ord-149089f0f8494b3ea8da63ae36c5d500
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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