HCID 10881778, compound → HCID 53888831, compound

Participants

Reaction Steps

Activated manganese dioxide (MnO2) (9.0 g) was added to a solution of (E)-3-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propen-1-ol (3.7 g) in dichloromethane (80 ml), which was stirred for one hour at room temperature. The reaction mixture was subjected to filtration through celite layer. The filtrate was concentrated under reduced pressure to give 4-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnamoaldehyde (2.6 g, 70%), which was recrystallized from ethyl acetate--hexane to yield colorless prisms, m.p.114°-115° C.

Provenance & Evidence