HCID 18546174, compound → HCID 18546119, compound

HRID 233297Notes

Reaction equation

HRID 233297 reaction equation
[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:20]=[CH:19][C:18](/[C:21](/[CH3:25])=[CH:22]/[CH2:23][OH:24])=[CH:17][CH:16]=1>[O-2].[O-2].[Mn+4]>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:16]=[CH:17][C:18](/[C:21](/[CH3:25])=[CH:22]/[CH:23]=[O:24])=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 18546174HCID 18546174, compound

Product 1

HCID 18546119HCID 18546119, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

According to the method described for Reference Example 34, (E)-3-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-buten-1-ol was subjected to oxidation with activated manganese dioxide to give (E)-3-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-buten-1-al. Recrystallization from ethyl acetate--hexane gave colorless prisms, m.p.94°-95° C.

Sources & evidence

ORD record
ord-c81ac86dc71c4949b6c2cd2300ae111c
Source dataset
uspto-grants-1997_01
Patent number
US05591862

Reaction notes

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