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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 233299Generated: October 28, 2026

Diisobutylaluminumhydride → (E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propenol

https://huagongshe.com/reaction/233299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisobutylaluminumhydrideHCID 21225700—
ReactantEthyl 3-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnamateHCID 53825120—
Product(E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propenolHCID 10860209—

Reaction Steps

According to the method described for Reference Example 23, ethyl 3-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnamate was subjected to reduction with diisobutylaluminum hydride to give (E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propen-1-ol. Recrystallization from ethyl acetate gave colorless prisms, m.p.120°-121° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05591862
Source datasetuspto-grants-1997_01
ORD IDord-365e897cea584c608ba2cc735885d5e3
Source noteuspto-grants-1997_01