Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 233301Generated: October 30, 2026

Diethyl (cyanomethyl)phosphonate → (E,E)-5-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienenitrile

https://huagongshe.com/reaction/233301

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (cyanomethyl)phosphonateHCID 75676—
Reactant(E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propen-1-alHCID 11834143—
Product(E,E)-5-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienenitrileHCID 23361384—

Reaction Steps

According to the method described for Reference Example 35, (E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2-propen-1-al was allowed to react with diethyl cyanomethylphosphonate to give (E,E)-5-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienenitrile as an oily product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05591862
Source datasetuspto-grants-1997_01
ORD IDord-548abeef98b74c07a3edaaa000799990
Source noteuspto-grants-1997_01