HCID 23361364, compound → HCID 23361355, compound

HRID 233305Notes

Reaction equation

HRID 233305 reaction equation
[CH3:1][C:2]1[S:6][C:5]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12](/[CH:15]=[CH:16]/[CH2:17][OH:18])=[CH:11][CH:10]=2)=[N:4][C:3]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>[O-2].[O-2].[Mn+4]>[CH3:1][C:2]1[S:6][C:5]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12](/[CH:15]=[CH:16]/[CH:17]=[O:18])=[CH:11][CH:10]=2)=[N:4][C:3]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 1

HCID 23361364HCID 23361364, compound

Product 1

HCID 23361355HCID 23361355, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

According to the method described for Reference Example 34, (E)-3-[4-(5-methyl-4-phenyl-2-thiazolylmethoxy)phenyl]-2-propen-1-ol was subjected to oxidation reaction with activated manganese dioxide to give (E)-3-[4-(5-methyl-4-phenyl-2-thiazolylmethoxy)phenyl]-2-propen-1-al. Recrystallization from ethyl acetate--hexane gave colorless prisms, m.p.116°-117° C.

Sources & evidence

ORD record
ord-7b0898171db24c3b9b411b21fa87ca8b
Source dataset
uspto-grants-1997_01
Patent number
US05591862

Reaction notes

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