Dimethyl Sulfoxide → 7'-Bromo-3'-methoxyspiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

HRID 2333098Notes

Reaction equation

HRID 2333098 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][cH:8]1)[C:5]21[CH2:17][O:18][CH2:19][C:20]([NH2:22])=[N:21]1.[CH3:23][O-:24].[CH3:26][S:27]([CH3:28])=[O:29].[Na+:25]>>[Br:1][c:2]1[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([O:24][CH3:23])[n:9][cH:8]1)[C:5]21[CH2:17][O:18][CH2:19][C:20]([NH2:22])=[N:21]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 3826051MethoxideHCID 584659017-Bromo-3-chloro-2',6'-dihydrospiro[chromeno[2,3-c]pyridine-5,3'-[1,4]oxazin]-5'-amine

Product 1

HCID 674392897'-Bromo-3'-methoxyspiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

Sources & evidence

ORD record
ord-681b1db9f583482aa3799f7bde9c0770
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…