1-(3,4,5-Trimethoxybenzyl)-3-(4-fluorophenylmethyl)-2-oxopyrrolidine → 3-(3-Dimethylsilyloxy-4,4-dimethylpentyl)-3-[(4-fluorophenyl)methyl]-1-[(3,4,5-trimethoxyphenyl)methyl]pyrrolidin-2-one
Reaction equation
[C:28]([CH3:29])([CH3:30])([CH3:31])[CH:32]([CH2:33][CH2:34][Br:35])[O:36][SiH:37]([CH3:38])[CH3:39].[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:20])[CH:9]([CH2:12][c:13]3[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]3)[CH2:10][CH2:11]2)[cH:21][c:22]([O:26][CH3:27])[c:23]1[O:24][CH3:25]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:20])[C:9]([CH2:12][c:13]3[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]3)([CH2:34][CH2:33][CH:32]([C:28]([CH3:29])([CH3:30])[CH3:31])[O:36][SiH:37]([CH3:38])[CH3:39])[CH2:10][CH2:11]2)[cH:21][c:22]([O:26][CH3:27])[c:23]1[O:24][CH3:25]Participants
3
Sources & evidence
- ORD record
- ord-393a5bdc9adf4d6497aad664ba1b43e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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