Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
benzyl (2S)-2-aminopropanoate → N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]alanine benzyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
| 반응물 | 2-Acetylthiomethyl-3-(4-hydroxyphenyl)butanoic acid | HCID 18980788 | — |
| 생성물 | N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]alanine benzyl ester | HCID 54412918 | 69% |
반응 단계
Using the procedure described in Example 60, but starting with 2-acetylthiomethyl-3-(4-hydroxyphenyl)butanoic acid and alanine benzyl ester, N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]alanine benzyl ester is obtained in a 69% yield, the characteristics of which are as follows: Rf= 0.22 [hexane/ethyl acetate (65:35 by volume)].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05591891 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-ba6031c10ed24dde85aae8303e12c2c9 |
| 출처 메모 | uspto-grants-1997_01 |