Acetic Acid → tert-butyl N-[3-[[5-amino-1-(benzenesulfonyl)pyrrolo[2,3-b]pyridin-4-yl]amino]cyclopentyl]carbamate

HRID 2333781Notes

Reaction equation

HRID 2333781 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH:10]([NH:13][c:14]2[c:15]3[c:16]([n:17][cH:18][c:19]2[N+:20]([O-:21])=[O:22])[n:23]([S:26](=[O:27])(=[O:28])[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:24][cH:25]3)[CH2:11][CH2:12]1)=[O:35].[CH3:38][C:39](=[O:40])[OH:41].[H:36][H:37].[OH-:42].[OH-:44].[Pd+2:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH:10]([NH:13][c:14]2[c:15]3[c:16]([n:17][cH:18][c:19]2[NH2:20])[n:23]([S:26](=[O:27])(=[O:28])[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:24][cH:25]3)[CH2:11][CH2:12]1)=[O:35]

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 67348748tert-butyl N-[3-[[1-(benzenesulfonyl)-5-nitropyrrolo[2,3-b]pyridin-4-yl]amino]cyclopentyl]carbamateHCID 178418361HCID 178418361, compound

Product 1

HCID 67345228tert-butyl N-[3-[[5-amino-1-(benzenesulfonyl)pyrrolo[2,3-b]pyridin-4-yl]amino]cyclopentyl]carbamate

Sources & evidence

ORD record
ord-fb4a819dbe8d4845a1fd7342ee6da1de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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