2-(2',3'-Dimethoxyphenyl)-1-furanylethanone → 2-(2',3'-Dimethoxyphenyl)-1-tetrahydrofuranyl ethanol

Participants

Reaction Steps

A solution of 450 mg (1.8 mmol) of 2-(2',3'-dimethoxyphenyl)-1-furanylethanone, from Step 2, and 20% palladium on carbon (225 mg) in 75 mL of methanol was shaken under 4 atmospheres of hydrogen until hydrogen uptake ceased. The solution was filtered and concentrated in vacuo to give 320 mg (69% yield) of the title compound as an oily solid. This product was carried on without purification to the next step.

Provenance & Evidence