7-Bromo-3-trifluoromethyl-imidazo[1,2-B][1,2,4]triazine → 2'-Fluoro-3'-(3-trifluoromethylimidazo[1,2-b][1,2,4]triazin-7-yl)biphenyl-2-carbonitrile

HRID 2334129Notes

Reaction equation

HRID 2334129 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[n:7][cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[n:10]2.[C:15](#[N:16])[c:17]1[c:18](-[c:23]2[c:24]([F:32])[c:25]([B:29]([OH:30])[OH:31])[cH:26][cH:27][cH:28]2)[cH:19][cH:20][cH:21][cH:22]1>>[c:2]1(-[c:25]2[c:24]([F:32])[c:23](-[c:18]3[c:17]([C:15]#[N:16])[cH:22][cH:21][cH:20][cH:19]3)[cH:28][cH:27][cH:26]2)[cH:3][n:4][c:5]2[n:6]1[n:7][cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[n:10]2

Participants

3

Reactant 2

HCID 116014167-Bromo-3-trifluoromethyl-imidazo[1,2-B][1,2,4]triazineHCID 11644397(2'-Cyano-2-fluoro-[1,1'-biphenyl]-3-yl)boronic acid

Product 1

HCID 101567802'-Fluoro-3'-(3-trifluoromethylimidazo[1,2-b][1,2,4]triazin-7-yl)biphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-4c75eb584ffe4b6193a36e9e319dff33
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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