Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 233426Generated: October 25, 2026

(+-)-Homocysteine → Captopril

https://huagongshe.com/reaction/233426

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-HomocysteineHCID 778—
ReactantMethylene blue cationHCID 4139—
ReactantL-(+)-CysteineHCID 5862—
ReactantN-Acetyl-L-CysteineHCID 12035—
ReactantGlutathioneHCID 124886—
ProductCaptoprilHCID 44093—

Reaction Steps

Glutathione, L-cysteine, DL-homocysteine, D-penicillin, hemoglobin Coovine), methylene blue and Medium 199 sets were purchased from Sigma Chemical Co., St. Louis, MO. N-acetylcysteine was obtained from Aldrich Chemical Co., Milwaukee, WI. Captopril was kindly provided by Dr. Victor Dzau. Sodium nitrite, histamine and methacholine were purchased from Fisher Scientific, Fairlawn,. N.J. Leukotriene D4 was purchased from Anaquest, BOC Inc., Madison, WI. Antibiotic/antimycotic mixture (10,000 U/ml penicillin G sodium, 10,000 mg/ml, streptomycin sulfate, 25 mg/ml amphotericin B) was purchased from Gibco laboratories, Grand Island, NY. Radioimmunoassay kits for the determination of cyclic GMP were purchased from New England Nuclear, Boston, MA.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05593876
Source datasetuspto-grants-1997_01
ORD IDord-165c625bc2a84912824c9ea45207da50
Source noteuspto-grants-1997_01