Methanol → [5-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-yl]methanol

HRID 2334330Notes

Reaction equation

HRID 2334330 reaction equation
[BH4-:29].[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[c:11]3[c:12]([n:13]1)[s:14][c:15]([CH:17]=[O:18])[n:16]3)[cH:25][cH:26][cH:27][cH:28]2.[CH3:31][OH:32].[Na+:30]>>[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[c:11]3[c:12]([n:13]1)[s:14][c:15]([CH2:17][OH:18])[n:16]3)[cH:25][cH:26][cH:27][cH:28]2

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 596058695-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine-2-carbaldehyde

Product 1

HCID 59605840[5-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-yl]methanol

Sources & evidence

ORD record
ord-64f3346674e84ceebb1ed9cef6b4bc08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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