2-(Bromomethyl)tetrahydro-2H-pyran → 1'-(2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)-2'-oxo-1',2'-dihydrospiro[1-benzofuran-3,3'-indole]-6-carbonitrile

HRID 2334356Notes

Reaction equation

HRID 2334356 reaction equation
[Br:13][CH2:14][CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19][O:20]1.[Cl:1][CH2:2][c:3]1[cH:4][c:5]2[c:6]([cH:11][cH:12]1)[O:7][CH2:8][CH2:9][O:10]2.[O:21]=[C:22]1[N:23]([CH2:41][c:42]2[cH:43][cH:44][cH:45][cH:46][n:47]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]2[C:30]12[CH2:31][O:32][c:33]1[c:34]2[cH:35][cH:36][c:37]([C:39]#[N:40])[cH:38]1>>[CH2:2]([c:3]1[cH:4][c:5]2[c:6]([cH:11][cH:12]1)[O:7][CH2:8][CH2:9][O:10]2)[N:23]1[C:22](=[O:21])[C:30]2([c:29]3[c:24]1[cH:25][cH:26][cH:27][cH:28]3)[CH2:31][O:32][c:33]1[c:34]2[cH:35][cH:36][c:37]([C:39]#[N:40])[cH:38]1

Participants

4

Reactant 3

HCID 1419172-(Bromomethyl)tetrahydro-2H-pyranHCID 52302876-(Chloromethyl)-2,3-dihydro-1,4-benzodioxineHCID 593524152'-Oxo-1'-(pyridin-2-ylmethyl)-1',2'-dihydrospiro[1-benzofuran-3,3-indole]-6-carbonitrile

Product 1

HCID 593525601'-(2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)-2'-oxo-1',2'-dihydrospiro[1-benzofuran-3,3'-indole]-6-carbonitrile

Sources & evidence

ORD record
ord-bc8f96f2d782400eae145175d263027c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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