1-(Bromomethyl)-4-(trifluoromethyl)benzene → N-Benzyl-3-methyl-5-(2-oxo-4-(4-(trifluoromethyl)benzyloxy)pyridin-1(2H)-yl)thiophene-2-carboxamide
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:9]([F:10])([F:11])[F:12])[cH:7][cH:8]1.[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[NH:20][C:21](=[O:22])[c:23]1[s:24][c:25](-[n:29]2[c:30](=[O:36])[cH:31][c:32]([OH:35])[cH:33][cH:34]2)[cH:26][c:27]1[CH3:28]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([C:9]([F:10])([F:11])[F:12])[cH:7][cH:8]1)[O:35][c:32]1[cH:31][c:30](=[O:36])[n:29](-[c:25]2[s:24][c:23]([C:21]([NH:20][CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)=[O:22])[c:27]([CH3:28])[cH:26]2)[cH:34][cH:33]1Participants
3
Sources & evidence
- ORD record
- ord-e0d9917d4d0f4e499092bcf6856579c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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