3-Hydroxyazetidine → 1-Benzhydryl-3-[2-(trifluoromethyl)benzhydryloxy]azetidine
Reaction equation
[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[C:13]1([OH:14])[CH:15]=[CH:16][CH:17]=[CH:18][CH2:19]1.[CH:38]([c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1)([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[N:51]1[CH2:52][CH:53]([O:55][CH:56]([c:57]2[cH:58][cH:59][c:60]([Cl:61])[cH:62][cH:63]2)[c:64]2[cH:65][cH:66][c:67]([Cl:68])[cH:69][c:70]2[Cl:71])[CH2:54]1.[F:20][C:21]([c:22]1[c:23]([CH:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[OH:31])[cH:32][cH:33][cH:34][cH:35]1)([F:36])[F:37].[NH:1]1[CH2:2][CH:3]([OH:4])[CH2:5]1>>[F:20][C:21]([c:22]1[c:23]([CH:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[O:31][CH:53]2[CH2:52][N:51]([CH:38]([c:39]3[cH:40][cH:41][cH:42][cH:43][cH:44]3)[c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[CH2:54]2)[cH:32][cH:33][cH:34][cH:35]1)([F:36])[F:37]Participants
5
Sources & evidence
- ORD record
- ord-35575515bd064238a55e5a382eb21e66
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…