1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol → Methyl 3-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH2:5][CH3:6])[c:7]([NH:8][CH:9]2[c:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[CH2:16][CH:17]2[OH:18])[n:19][c:20]1[CH2:21][CH3:22].[CH3:23][O:24][C:25](=[O:26])[N:27]1[CH2:28][CH:29]([NH:36][c:37]2[n:38][c:39]([CH2:45][CH3:46])[cH:40][n:41][c:42]2[CH2:43][CH3:44])[CH:30]([O:32][CH2:33][CH2:34][F:35])[CH2:31]1>>[Br:1][c:40]1[c:39]([CH2:45][CH3:46])[n:38][c:37]([NH:36][CH:29]2[CH2:28][N:27]([C:25]([O:24][CH3:23])=[O:26])[CH2:31][CH:30]2[O:32][CH2:33][CH2:34][F:35])[c:42]([CH2:43][CH3:44])[n:41]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a106f0dfbc2f403881161d2cd4422eac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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