Methanol → 3-[2'-([1,2,4]Triazol-1-yl)biphenyl-3-yl]-7-trifluoromethylimidazo[1,2-a]pyrimidine

HRID 2335571Notes

Reaction equation

HRID 2335571 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[c:9](-[n:14]3[n:15][cH:16][n:17][cH:18]3)[cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1.[CH2:19]([Sn:20]([CH2:21][CH2:22][CH2:23][CH3:37])([c:24]1[cH:25][n:26][c:27]2[n:28]1[cH:29][cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[n:32]2)[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[CH3:45][OH:46].[Cl:47][CH2:48][Cl:49]>>[c:2]1(-[c:24]2[cH:25][n:26][c:27]3[n:28]2[cH:29][cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[n:32]3)[cH:3][c:4](-[c:8]2[c:9](-[n:14]3[n:15][cH:16][n:17][cH:18]3)[cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 11294484Imidazo[1,2-a]pyrimidine, 3-(tributylstannyl)-7-(trifluoromethyl)-HCID 180012791-(3'-bromobiphenyl-2-yl)-1H-[1,2,4]triazole

Product 1

HCID 101794683-[2'-([1,2,4]Triazol-1-yl)biphenyl-3-yl]-7-trifluoromethylimidazo[1,2-a]pyrimidine

Sources & evidence

ORD record
ord-2a01ed4f302c49feb6ffe8489fae09eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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